Canadian pharmaceutical billionaire Barry Sherman and his wife, Honey, were found dead on a Friday in their North York, Toronto, home, prompting an investigation by the Toronto police homicide squad. Police described the deaths as suspicious and said both died from ligature neck compression. Local reports said a real estate agent discovered their bodies hanging near an indoor pool. Police reported no signs of forced entry and said they were not searching for suspects who posed a danger to the public.

Some media outlets cited police sources suggesting a possible murder-suicide, but the Shermans’ four grown children rejected that theory. In a statement, the family said their parents’ enthusiasm for life and commitment to family and community were inconsistent with the speculation. Friends and colleagues also expressed disbelief. Police said they could not yet say with certainty whether foul play was involved.

Friends said Honey Sherman had been making plans shortly before her death for the couple’s annual trip to Florida, including a dinner party at their Palm Beach home. She was remembered as warm, sociable and dedicated to philanthropy. Her charitable work included service with York University, the Baycrest Foundation, Mount Sinai Hospital and organizations supporting the Jewish community.

Barry Sherman, 75, founded generic-drug manufacturer Apotex in 1974 and built it into an international business. Canadian Business recently estimated his net worth at $4.77 billion, ranking him among Canada’s richest people. Friends described him as intensely devoted to his work, while Toronto Mayor John Tory praised his investment in the city and the jobs Apotex created.

Tributes came from political leaders, friends, former employees and members of Toronto’s Jewish community. The couple donated millions to hospitals, universities and charitable causes, and mourners left flowers outside their home. Their deaths left those who knew them shocked and searching for answers.