Canadian pharmaceutical billionaire Barry Sherman, 75, and his wife, Honey, 70, were found dead on Friday at their Toronto home. Police said both died from ligature neck compression and described the deaths as suspicious. Homicide detectives were leading the investigation, but police had not classified the deaths as homicides or determined whether foul play was involved.

The couple were found hanging from a railing near their indoor pool, according to local reports. A real estate agent who was handling the sale of their North York home reportedly discovered them. Police sources said there were no signs of forced entry, and police said they were not searching for outstanding suspects.

Some news reports cited police sources suggesting a possible murder-suicide. The Shermans’ four children rejected that theory, saying their parents’ enthusiasm for life and commitment to family and community were inconsistent with the rumours. Friends also expressed disbelief. Shortly before the deaths, Honey had made plans for the couple’s annual trip to Florida and invited friends to get together there.

Barry Sherman founded generic-drug manufacturer Apotex in 1974 and built it into an international business. Canadian Business recently estimated his fortune at $4.77 billion, ranking him 15th among Canada’s richest people. Friends and colleagues remembered him as a dedicated workaholic who had no plans to leave the company. Toronto Mayor John Tory praised his investment in the city and the jobs Apotex created.

Honey Sherman was remembered as outgoing and deeply committed to philanthropy. The couple gave millions to hospitals, universities and Jewish community causes. She served on the boards of organizations including the Baycrest Foundation and York University Foundation and was involved with Mount Sinai Hospital and other charitable groups.

Their deaths prompted tributes from political leaders, friends, employees and community members. Well-wishers left flowers outside the couple’s home, while those who knew them struggled to understand what had happened.